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However, the inflammatory response is the primary mechanism by which these participate in the harmful effects process of toxicants through the SIRT1/NF-B pathway 128

Additionally, glutathione is used for its skin-lightening properties, as it inhibits the enzyme tyrosinase, which is involved in the production of melanin

Melanoacanthoma has been reported in labial mucosa, palate, gingiva, alveolar mucosa and oropharynx (Table 1)

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This results in a reduction of procaspase-3 and caspase-1 expression levels