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A new signal: dysesthesia with retatrutide The TRIUMPH-4 Phase 3 trial revealed a side effect not previously highlighted in earlier data

Furthermore, tirzepatide has shown longer titration periods in clinical practice, delaying attainment of full maintenance doses and potentially dampening early cardiovascular benefits 28

The Critical Role of Lifestyle Factors You cant expect tirzepatide to do all the work when it comes to weight loss

As with any medication, side effects like nausea, mild gastrointestinal discomfort, or loss of appetite may occur initially but typically lessen over time