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Semaglutide is Neuroprotective and Reduces -Synuclein Levels in the Chronic MPTP Mouse Model of Parkinsons Disease

In a clinical setting, the loss of lean mass associated with some IF protocols, could exacerbate sarcopenia in older adults or individuals with chronic conditions and compromise cardiovascular resilience

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Diabetes Obes Metab 14:514 Dormandy JA, Charbonnel B, Eckland DJ, Erdmann E, Massi-Benedetti M, Moules IK, The PROactive Investigators (2005) Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive study (PROspective pioglitAzone clinical trial in macro vascular events): a randomised controlled trial