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Abstract Objectives: This study aims to explore the weight loss effect and safety of semaglutide as a conventional anti-obesity drug systematically in obese or overweight patients without diabetes

found that apoptosis is caused by the release of cytochrome c from the mitochondria, leading to the cleavage of caspase 3 and PKC and finally DNA fragmentation (Latchoumycandane et al., 2005)