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But most of these alleged benefits come from early research, animal studies, or anecdotal reports not large, high-quality human clinical trials

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Hepatology 66 , 809824 (2017)

This could indicate higher than normal levels of oxidative stress in virus-infected SA-deficient tobacco cells in later stages of pathogenesis (5 days after inoculation, DAI) when necrotic (HR) lesions are fully developed, even if glutathione accumulation and TMV resistance is comparable to that of wild type plants