Higher retatrutide doses (10-12 mg) produce more GI side effects and carry a higher risk of dysesthesia (tingling/numbness) without engaging the amylin pathway
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To detect GLP1-induced FNDC5 expression in mouse pancreas and brain tissue, C57BL/6 mice were fed with chow diet and randomly divided into two groups, and treatment with either liraglutide or saline as control were given once daily by i.p
