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Improvements to hair and skin usually follow months of consistent spironolactone treatment, not weeks

TGF1, transforming growth factor beta 1

This trial used the DAC version, not No DAC

Clinical implications Patients with T2DM and AF have higher mortality rates and cardiovascular complications than those in sinus rhythm, with thromboembolism being the most significant risk factor [2]

*Correspondence: Richard Eugene Frye, Arkansas Childrens Hospital Research Institute, Slot 512-41B, 13 Childrens Way, Little Rock, AR 72202, USA e-mail: [email protected] This article was submitted to Child and Neurodevelopmental Psychiatry, a section of the journal Frontiers in Pediatrics