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Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1

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Pancreatitis, gallbladder events, and increased heart rate were noted as risks requiring monitoring

If confirmed, this would be a significant tolerability advantage

It is important to note that while Mounjaro is administered subcutaneously and its absorption is not affected by gastric sleeve surgery, its mechanism of slowing gastric emptying could potentially compound post-surgical changes in gastrointestinal function