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When co-cultured with a human-derived monocyte line with normal G6PD activity, HUVECs rendered G6PD-d via inhibition with 6-AN, dehydroepiandosterone (DHEA), or G6PD knockdown displayed increased monocyte adhesion

While the driving force behind these conditions is the body attacking itself (autoimmunity), they can show up in the body in so many different ways Hashimotos is an attack on the thyroid, multiple sclerosis is an attack on the nervous system, alopecia attacks the hair follicles, and so on

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J Transl Med 24 , 265 (2026)

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