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The turbulence created by shaking generates mechanical shear forces strong enough to break the amide bonds linking amino acids together, which alters the peptides three-dimensional structure in a way that cant be undone

Nature 420 , 686690 (2002)

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Existe deficiencia secundaria de levocarnitina por: Falta de sntesis y/o aporte (nutricin artificial, desnutricin o malos hbitos de alimentacin, prematuros, neonatos y nios de bajo peso, lactantes alimentados con frmulas de soya o casena, vegetarianismo estricto, cirrosis heptica)