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In a more recent review from 2024 comprising patients with bipolar disorder from North America, Europe and Australia, antidepressants were prescribed cross-sectionally for 38%, being among the most prescribed medications [11]

The hydroxyl groups of CD allow structural modifications yielding hydrophobic derivatives, namely acylated and ethylated cyclodextrins, that may be used to achieve a sustained release of the drugs

*Correspondence: Ze Wang, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Fact: Effective wellness is about absorption, not just dosage

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