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Ferroptosis, introduced by Dixon in 2012, is an iron-dependent form of programmed cell death (PCD) that primarily impacts cellular organelle structures, particularly mitochondrial architecture, and is marked by the buildup of lipid peroxides [51,52]

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Why the Absence of Data Matters The absence of evidence is not proof of safety, but it is informative

Figure 1 Patients with GSSD, which is classified as mild, moderate, or severe based on clinical symptoms, usually show disease onset symptoms during the neonatal period ( 2