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Dendritic spine density was measured on primary and secondary dendrites, and spine-head width was also assessed

Emerging approaches advocate for a paradigm shift, integrating multimodal biomarkers, such as neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), tau protein (Tau), with in vivo imaging (fMRI, and PET), AI-driven patient stratification and adaptive trial designs

Ferroptosis as a Novel Therapeutic Target for Friedreichs Ataxia

This is a theoretical concern from epidemiological data, not a demonstrated side effect of CJC-1295, but it warrants monitoring (Renehan et al., Lancet 2004)

The peptide extends the anagen (growth) phase while shortening both catagen (regression) and telogen (rest) phases of the hair cycle