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SGLT-2 inhibitors were superior to GLP-1RA in reducing the risk of HHF and the renal outcome (24% and 22% lower risk, respectively)

135 MorrisG.MaesM

So, we have a fairly constructive view, perhaps an optimistic view

Lm sch mt

Despite its pleiotropic mechanisms, resveratrols clinical translation has been hindered by pharmacokinetic limitations, such as rapid hepatic metabolism, poor aqueous solubility, and low bioavailability, which collectively undermine its therapeutic efficacy [3]