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Recent data indicate that UC affects approximately 5 million individuals worldwide as of 2023, with a steadily rising incidence rate (Ramos and Papadakis, 2019)
Additional benefits include improved mood, cognitive function, and better mobility in peripheral artery disease
Hormonal Changes : Factors such as pregnancy, hormonal therapies, or conditions like melasma can alter melanin production
In hypertensive patients, abnormal histone acetylation and methylation are commonly observed, impacting vascular smooth muscle cell proliferation and function [76]
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