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If you are participating in a clinical trial or receiving retatrutide under specialist supervision, any decision to pause or stop treatment should be discussed with your study team or supervising clinician

However, the challenge with current TRPV1 antagonists lies in their associated adverse effects, such as hyperthermia 24,25,26,27,28,29,30,31 and hypothermia 32,33,34 , caused by failures in thermoregulation

Researchers have explored DSIP for possible effects on sleep regulation, stress response, pain signaling, endocrine function, and nervous system activity

Gastrointestinal effects : GLP-1 receptor agonists as a class are well known to cause nausea, vomiting, and delayed gastric emptying

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