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In a pediatric clinical trial for weight reduction, 2.3% of patients treated with WEGOVY versus 1.5% of patients who received placebo discontinued treatment as a result of gastrointestinal adverse reactions

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This distinction matters because the approach to breaking through differs dramatically based on where you are in treatment

Wang LL, Qi HB, Baker PN, Zhen QN, Zeng Q, Shi R, Tong C, Ge Q (2017) Altered circulating inflammatory cytokines are associated with anovulatory polycystic ovary syndrome (PCOS) women resistant to clomiphene citrate treatment