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Topical application of GHK-Biotin is not an attempt to override the body's natural processes it is a means of replenishing a molecule that the body itself once produced in abundance, delivered precisely where it is needed, at the tissue level, bypassing the absorption and bioavailability challenges inherent in oral supplementation

Specifically for MET-097i, key structural modifications include: 1) Substitution of Alanine2 with AIB (aminoisobutyric acid) to prevent DPP-4 degradation

Fasting triglycerides decreased by up to 35%

While these drugs are typically injected, some patients may desire an alternative method of administering

doi: 10.1016/j.metabol.2013.09.010 12 SchirraJNicholausMRoggelRKatschinskiMStorrMWoerleHJet al