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Methods Gene expression profiles were downloaded from the Gene Expression Omnibus, and batch-corrected and normalized expression data were obtained using the ComBat package

The levels of glutathione decrease naturally with age, as well as with certain stressors, including exercise, smoking, and pollution

During training, a large portion of L-carnitine within mitochondria is converted into ALC through the enzyme carnitino-acetyl transferase

Consider the following: Diet: Incorporate foods rich in glutathione precursors, such as cruciferous vegetables (broccoli, kale), garlic, onions, and lean proteins

Synapsin-Cre + male mice were mated to Gipr fl/fl female mice (previously described 17 ) to generate mice with heterozygous floxed Gipr gene with or without the synapsin-Cre transgene