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The peptide is constructed on a GIP receptor backbone with non-coded amino acid residues (Aib2, Aib20, aMeL13) and a C20 fatty diacid moiety that enables albumin binding, extending pharmacokinetic half-life for once-weekly administration in research settings

For individuals who use anti-inflammatory medications, BPC 157 may help protect the gut from potential side effects

It may pose a different sort of hurdle, though, and that's the taste

Role of ppar alpha in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator wy-14,643

doi: 10.2337/dc21-1351 144 RoglianiPCalzettaLCapuaniBFaccioloFCazzolaMLauroDet al