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Bone fragility in diabetes: novel concepts and clinical implications

The STAT3 factors induce the expression of SOCS proteins which consequently inhibit the function of JAK/STAT3 signaling, i.e., SOCS proteins exert a negative feedback on the JAK/STAT3 signaling induced by both insulin/IGF-1 and certain cytokine pathways

Potential mechanisms of the protective effects of the cardiometabolic drugs type-2 sodiumglucose transporter inhibitors and glucagon-like peptide-1 receptor agonists in heart failure