injections of 100 nmol kg 1 MK-801 ( n = 7 mice and n = 4 cages), 100 nmol kg 1 GLP-1 ( n = 6 mice and n = 3 cages), 100 nmol kg 1 , GLP-1MK-801 ( n = 6 mice and n = 3 cages), co-administration of 100 nmol kg 1 GLP-1 and 100 nmol kg 1 MK-801 ( n = 6 mice and n = 3 cages) or vehicle (isotonic saline, n = 7 mice and n = 4 cages) for 14 days
If you believe you are experiencing a medical emergency, call 911 or go to the nearest emergency room immediately.
GLP-1 stands for glucagon-like peptide-1, a hormone your gut naturally releases after eating
The bone health implications are particularly concerning for women over 40, post-menopausal women, and anyone with a family history of osteoporosis
Rapid weight loss can be associated with reductions in bone mineral density, which is of particular relevance to perimenopausal and postmenopausal women who are already at increased risk of osteoporosis