According to the Phase 3b, double-blind, placebo-controlled STRIDE study, Ozempic (1 mg) resulted in a superior and clinically meaningful improvement of 13% in maximum walking distance and a mean treatment difference of 39.9 meters on a steep incline compared to placebo at week 52 in adults with T2DM and PAD. If approved, Ozempic will be the only GLP-1 receptor agonist indicated for the treatment of PAD in patients with T2DM
The anti-inflammatory effects associated with weight loss and metabolic improvement may also be beneficial, as chronic inflammation plays a role in AMD pathogenesis
Hyaluronic acid as a non-invasive biomarker of liver fibrosis
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