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Emerging Role of GLP-1 Agonists in Obesity: A Comprehensive Review of Randomised Controlled Trials

Slower titration almost always improves tolerability with both compounds

As Habener explains, 'Previous studies in animals had shown that GLP-1 slowed down acid secretion and stomach emptying and caused early satiety

There is large inter-person variability in response to GLP1 medications both in terms of weight loss and side effects, with the two potentially being related (that is, people who experience more nausea may lose more weight 30 )