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Conclusion By focusing on the ROS-related PIPN mechanism, both antioxidant drugs (e.g., small molecular drugs, traditional medicines/active ingredients) and tailor-made nanosystems (e.g., tumor-targeting Pt nanosystems and anti-ROS nanosystems) have demonstrated to be effective in the prevention and treatment of PIPN

Tambuwala, Email: [email protected] References Ahmed KSZ, Ahmed SSZ, Thangakumar A, Krishnaveni R

Key Takeaway: Bioavailability is the most critical factor in glutathione supplementation

The use of these agents is increasing based on recommendations from the American Diabetes Association and the European Association for the Study of Diabetes

The corresponding graph is presented in figure 7