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Comparatively, 32,336 GLP-1 receptor agonists and 96,212 SGLT-2 inhibitor users were followed for a median of 1.2 and 1.2 years, respectively

Semaglutide is a synthetic GLP-1 RA (receptor agonist)

GLP-1: The Glucose Homeostasis Master Regulator The foundational understanding of how endogenous GLP-1 regulates blood glucose slowing gastric emptying, enhancing glucose-dependent insulin secretion, suppressing glucagon comes from decades of incretin research

For adults over 40, the maintenance phase is not a passive thing it requires conscious decisions about whether to stay on a maintenance dose, taper down, or come off entirely

At Cape Fear Physical Medicine and Rehab, we understand that managing chronic conditions like obesity often requires a comprehensive approach