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Enrollment, follow-up, data analysis, NDA (New Drug Application) preparation, and FDA review typically add up to 18-36 months even with Breakthrough Therapy Designation, which Lilly has received for retatrutide in obesity

Risk of stroke and retinopathy during GLP-1 receptor agonist cardiovascular outcome trials: an eight RCTs meta-analysis

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GLP-1 and Blood Pressure: What the Evidence Shows GLP-1 receptor agonists, primarily licensed for type 2 diabetes and obesity management, have demonstrated modest blood pressure-lowering effects in clinical trials