10.1002/ehf2.12003 77 HuangW
Mann JFE, Orsted DD, Brown-Frandsen K, Marso SP, Poulter NR, Rasmussen S, Tornoe K, Zinman B, Buse JB, Committee LS, Investigators
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While no direct head-to-head trials have compared oral semaglutide with injectable semaglutide at diabetes doses, indirect comparisons across clinical trials suggest that injectable formulations generally provide greater efficacy for both glycemic control and weight reduction
A small percentage of users report that the medication itself causes drowsiness, though this is not a documented side effect in major clinical trials