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From 1924 several researchers began to investigate the effect of injected and orally administered duodenal (secretin) extracts on fasting blood glucose levels and hyperglycemia (high blood sugar) in normal and diabetic animals and humans

doi: 10.1007/s13300020-009810 71 Marn-PealverJJMartn-TimnISevillano-CollantesCCaizo-GmezFJD

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Current research also explores how retatrutide affects glucose metabolism and energy use, which are critical for understanding its impact on metabolic health

In the last few years, studies have linked GLP-1 drugs like Ozempic and Wegovy with fewer cravings for alcohol, along with lower risks of substance use disorders involving alcohol, cannabis, and nicotine