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Alteration of ATG genes have been found in diabetic mouse models, including the deletion of Atg5 and Atg7 in PTECs, which is associated with the accumulation of damaged mitochondria, tubular cell apoptosis and renal fibrosis (108)

In conclusion, the present study identified alterations of small effect size in blood levels of short-chain ACs related to the presence and severity of depression, especially of clinical profiles expressing symptoms reflecting altered energy homeostasis

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