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73 During pathogenesis, inflammasomes are activated in response to damage-associated molecular patterns and pathogen-associated molecular patterns, releasing proinflammatory cytokines such as IL-1 and IL-18

Int J Environ Res Public Health 2021;18:7744.ArticlePubMedPMC 241

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This combination makes it relevant not just for aesthetic outcomes but for the broader inflammatory burden that accelerates aging in metabolically active tissues