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Topical copper-peptide delivery has a documented limitation worth stating plainly: the skin barrier limits how much of a peptide reaches the dermis

(1997) Biochemistry 36 : 6437-6447 PubMed: 9174360 Search on PubMed DOI: Primary Citation Related Structures: 1GRT, 2GRT, 3GRT, 4GRT, 5GRT PubMed Abstract: Trypanosoma and Leishmania, pathogens responsible for diseases such as African sleeping sickness, Chagas' heart disease, or Oriental sore, are two of the very few genera that do not use the ubiquitous glutathione/glutathione reductase system to keep a stable cellular redox balance

If this worries you, talk to your doctor or pharmacist about other options

Five more peptides are scheduled for a later PCAC meeting before the end of February 2027

But you should avoid a push if you: are pregnant or breastfeeding have asthma have a known glutathione allergy Although rare, an allergic reaction to glutathione might include swelling, hives, or trouble breathing