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There was a 50% increase in Tom-20 in the SE offspring, although without statistical significance (Figure 7F)

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Another trial in 54 individuals confirmed its safety over 10 days of intravenous use at doses of up to 5.0g/kg (and up to 25.0g/kg in a single-dose trial)

Importantly for weight management, semaglutide also affects areas of the brain that control appetite, helping you feel fuller for longer and reducing hunger