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Stacking multiple GLP-1 agonists together, such as semaglutide and tirzepatide, is generally not recommended due to overlapping mechanisms and increased side effect risk

Whilst the NHS notes that taking up to 2,000 micrograms daily is unlikely to cause harm in most people, there is generally no benefit to consuming such excessive amounts unless treating confirmed deficiency under medical supervision

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It functions in cellular signaling and lipid metabolism and has a role in serotonin signaling, which is the basis for the frequent claim that it curbs appetite