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During mastication they are enzimatically converted into thiocyanates, goitrin metabolites, that cause a competitive inhibition of the sodium/iodide symporter, thus inhibiting the thyroid hormones synthesis and possibly causing hypothyroidism [156]

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Induction of heme oxygenase-1 inhibits NAD(P) H oxidase activity by down-regulating cytochrome b558 expression via the reduction of heme availability

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