If you are eating far less, skipping meals, or avoiding food because of nausea, your body may respond with weakness, shakiness, lightheadedness, or difficulty concentrating
Patients should begin shifting focus during their final months of treatment toward building three non-negotiable habits: consistent protein intake (25-35% of daily calories) to preserve muscle and satiety, regular movement that combines strength training and cardiovascular activity at least 150 minutes weekly, and established meal timing patterns that prevent extreme hunger spikes
H., Wang, C
Beyond systemic metabolic effects, GLP-1 RAs may also modulate immune responses relevant to HS, though the precise mechanisms remain to be elucidated
The GLP-1R is expressed on a small subset of murine intrahepatic endothelial and T cells, and genetic elimination of Glp1r in these cells attenuated the anti-inflammatory actions of semaglutide in the livers of HFD-fed mice [120]