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38 These studies have led to guideline changes, in which GLP-1RA and SGLT-2i are now preferred glucose-lowering drugs (regardless of HbA1c level) in T2D patients with established cardiovascular disease or renal disease and are preferred second-line medications in patients at high cardiovascular risk, 3,22 i,e, patient groups that may constitute over a third of all people with T2D

This usually leads to eating less and losing weight when the medicine is used along with healthy habits