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Together, they create synergistic GH pulsatility through dual-pathway stimulation that ends up being far greater than either compound alone

Molecular communication from skeletal muscle to bone: a review for muscle-derived Myokines regulating bone metabolism

GHK-Cu is a copper-binding peptide that up-regulates collagen and elastin synthesis while down-modulating matrix metalloproteinases (MMPs), driving skin remodeling and connective-tissue repair

For a target organ as accessible from the outside as the skin, routing a copper complex through the whole body to reach it is arguably the least efficient and highest-exposure way to do it

In a way it's the secret to glutathione's function and success