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2123 This C-H/D biomolecular substitution occurs due to the rapid intracellular biocatalytic exchange between D of D 2 O and H atom of Nicotinamide Adenine Dinucleotide Phosphate (NADPH) which is redox active

Lancet 2 , 319323 (1967)

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x CT = any C-terminal amino acid) in the cytosolic tail of type I membrane protein clients, which leads to client packaging into COPI-coated vesicles and retrieval to ER 34,35,36,37,38,39,40