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Parker VER, Robertson D, Wang T et al (2020) Efficacy, safety, and mechanistic insights of cotadutide, a dual receptor glucagon-like peptide-1 and glucagon agonist

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More recently, high concentrations of bile acids have been associated with increased GLP-1 concentrations and glycaemic improvements, which might be mediated through nuclear farnesoid-receptor X (FXR) and the G-protein-coupled bile acid-activated receptor (TGR5) on enteroendocrine L cells [14]

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