retinopathy glp 1 GLP-1 Drugs and Diabetic Eye Disease: Ozempic, Semaglutide, and Risk Updated guidance from the PCDS

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J Urol 184:715720

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Hydrogen peroxide produced by neutrophils is used mainly by MPO which catalyzes oxidation reactions with the involvement of chlorine ions to produce hypochlorous acid (HOCl), hydroxyl radicals (OH ), singlet oxygen (O 2 1 ), and ozone (O 3 ) with strong bactericidal properties ( 2 - + H 2 O 2 OH - + OH - + O 2 ) and the Fenton reaction (H 2 O 2 + Fe 2+ Fe 3+ + OH - + OH - ) with the participation of pro-oxidant ions of transition metals (mostly Fe 2+ /Cu 2+ ) (51)