For individuals looking to bulk or recover from catabolic states, this is highly desirable
The most common are gastrointestinal: Nausea the most frequently reported side effect, especially during dose increases Vomiting less common than nausea, but can occur during titration Diarrhea typically mild and temporary Constipation some patients experience this instead of or in addition to diarrhea Decreased appetite this is both a therapeutic effect and something patients notice as a side effect These side effects are generally most noticeable in the first few weeks of treatment or after a dose increase, and tend to improve as the body adjusts
"CagriSema Phase 3 REDEFINE Trial Results." Company press release and investor presentation
Similarly, common types of gastric premalignant lesions are comprised of gastric ulcers, gastric polyps, atrophic gastritis, intestinal metaplasia, etc
A meta-analysis of 12 observational studies (5 prospective cohort studies, 4 case-control studies, and 3 cross-sectional studies) also found blood concentrations of selenium to be inversely associated with risk of stroke (94)