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In respiratory disease, clinicians may consider lung function testing and imaging

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Cereda E, Pedrolli C, Klersy C, Bonardi C, Quarleri L, Cappello S, et al

Recently, administration of the AdipoR agonist AdipoRon was found to effectively reduce the levels of the pro-inflammatory factor tumor necrosis factor (TNF-) and mitigate disc degeneration ( 2.3 Progranulin PGRN, a secreted glycoprotein that can be cleaved into granulins by enzymes like elastase, exerts anti-inflammatory effects and plays protective roles by enhancing cell proliferation and through interacting with TNF receptors (TNFRs) or other receptors

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