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Women with PCOS and excess weight can experience improved fertility The most encouraging data are in women with PMOS (formerly PCOS) and higher BMI

If you need a broader starting point, the sites What Is Retatrutide explainer gives more background on why researchers are watching this drug class

Gerstein HC, Sattar N, Rosenstock J et al

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Singularly, BBB impermeable mimics of GLP-1 have still shown to activate GLP-1 Receptor expressing neurons (165), but they require a functional gut-brain axis through the vagus nerve (166)