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MSH also reduced activation of fibroblasts, as measured by SMA staining (161), reduced inflammatory markers like TNF--induced activation of NFB (179) or IL-1-induced IL-8 release (181), as well as it conferred cytoprotection under inflammatory stimuli like IL-1, LPS and TNF- (180)

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[CrossRef] [PubMed] [Google Scholar] Expression of glycosaminoglycans and small proteoglycans in wounds: Modulation by the tripeptide-copper complex glycyl-Lhistidyl-L-lysine-Cu(2+) J Invest Dermatol