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Proc Natl Acad Sci U S A 1989;86:39537.ArticlePubMedPMC 29
The improvement in both HS-PGA and DLQI was possibly due to combined actions of weight loss and GLP-1 receptor activation
Its a powerful tool when paired with healthy lifestyle changes (diet and exercise)
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Some experts note that better mental health often follows improvements in physical health, making it difficult to disentangle whether GLP-1 drugs have unique neurobiological effects or whether benefits arise from downstream consequences like weight loss and stabilized blood sugar
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