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Samples were fixed in 10% buffered formalin overnight at 4C, dehydrated with increasing concentrations of ethanol, embedded in paraffin, cut into 5 m sections, and stained with hematoxylin and eosin (HE) or Massons Trichrome Stain Kit (Sigma-Aldrich)
Because of its strong engagement with the glucagon receptor, Survodutide effectively "uncondenses" energy stored in the liver, making it a prime subject for metabolic flexibility research
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