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PMID: 35951740 DOI: 10.1080/17512433.2022.2112948 Piwnica D et al (2014): Vasoconstriction and anti-inflammatory properties of the selective alpha-adrenergic receptor agonist brimonidine

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Heffernan M, Summers RJ, Thorburn A, Ogru E, Gianello R, Jiang W-J, et al

While undergoing chemotherapy, a double mastectomy, and five weeks of radiation, I exercised and managed my food intake like my life depended on it, because I knew it did

However, the study authors emphasize that more research is needed to confirm these mechanisms and determine whether the survival benefit observed in this real-world analysis represents a direct anti-cancer effect or an indirect result of improved metabolic health