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doi: 10.3390/v10080392 144 KlokF

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In summary, we conclude that cystinosin(7)-GFP is recognized by the ER lumenal chaperones, ubiquitinated by the ER membrane E3 ligase HRD1, and extracted by the cytosolic p97 ATPase before its degradation at the proteasome, hence following every step of the well-established ERAD pathway

Because Vitamin C is water-soluble, it cannot be stored in the body for later use

Many children with ASD follow specific diets, often because caregivers report that dietary interventions correlate with improvements in behaviors or medical symptoms (such as reflux, diarrhea, abdominal pain, or eczema)