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2003 [9] Lu SC

Gago, B., Lundberg, J

For your body to make sufficient amounts, you also need adequate amounts of vitamin C, iron and vitamins B3 and B6

Under normal circumstances, insulin maintains the NAD(+)/NADH ratio by activating the phosphoinositide 3-kinase/protein kinase B (PI3K/AKT) pathway and inhibiting the forkhead box protein O1/heme oxygenase 1 (Foxo1/Hmox1) pathway, thereby mediating the activation of the sirtuin 1/peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (SIRT1/PGC-1) pathway and regulating mitochondrial physiological functions (27)

CoQ10 is a naturally occurring compound involved in cellular energy production and antioxidant protection, with endogenous production declining with age